Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 9/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153054 | 1.00 | CBLB (0.41) | CBLBCYP11B2IDH1CEPT1CETP | |
| SCHEMBL24818967 | 1.00 | CBLB (0.41) | CBLBCYP11B2IDH1CEPT1CETP | |
| SCHEMBL30792046 | 0.91 | MAP3K5 (0.34) | CBLBCYP11B2KCNH2MAP3K5KDM4E | |
| SCHEMBL24820582 | 0.91 | MAP3K5 (0.34) | CBLBCYP11B2KCNH2MAP3K5KDM4E | |
| SCHEMBL30152957 | 0.91 | MAP3K5 (0.34) | CBLBCYP11B2KCNH2MAP3K5KDM4E | |
| SCHEMBL24820138 | 0.90 | MAP3K5 (0.34) | CBLBGLP1RKCNH2MAP3K5ALDH1A1 | |
| SCHEMBL30153076 | 0.90 | MAP3K5 (0.34) | CBLBGLP1RKCNH2MAP3K5ALDH1A1 | |
| SCHEMBL30792001 | 0.90 | MAP3K5 (0.34) | CBLBGLP1RKCNH2MAP3K5ALDH1A1 | |
| SCHEMBL24820567 | 0.88 | CBLB (0.41) | CBLBCYP11B2CETPKDM4EALDH1A1 | |
| SCHEMBL30792199 | 0.88 | CBLB (0.41) | CBLBCYP11B2CETPKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |