Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | LOX | P28300 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CBLB | Q13191 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | CCNK | O75909 | 2/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820416 | 1.00 | HDAC4 (0.44) | HDAC4PDK2LOXL2LOXRAB9A | |
| SCHEMBL24820337 | 1.00 | HDAC4 (0.44) | HDAC4PDK2LOXL2LOXRAB9A | |
| SCHEMBL24820335 | 0.84 | HPGD (0.43) | HDAC4RAB9ANPC1KMT2AHPGD | |
| SCHEMBL24820414 | 0.80 | ACACB (0.45) | KMT2A | |
| SCHEMBL24820342 | 0.75 | ALDH1A1 (0.44) | SCN9A | |
| SCHEMBL24820340 | 0.75 | ALDH1A1 (0.44) | SCN9A | |
| SCHEMBL24820338 | 0.75 | ALDH1A1 (0.44) | SCN9A | |
| SCHEMBL24821729 | 0.75 | TDP1 (0.47) | RAB9ANPC1HSP90AA1HPGD | |
| SCHEMBL13122951 | 0.75 | PDK2 (0.54) | HDAC4PDK2LOXL2LOXHSP90AA1 | |
| SCHEMBL21200128 | 0.69 | LOXL2 (0.50) | HDAC4PDK2LOXL2LOXCBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |