Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 12/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153103 | 1.00 | CBLB (0.42) | CBLBCETPCYP11B1CYP11B2MAP3K5 | |
| SCHEMBL30153166 | 0.88 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL24820110 | 0.88 | KDM4E (0.34) | CBLBCYP11B1 | |
| SCHEMBL24818907 | 0.88 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL30152997 | 0.87 | CBLB (0.43) | CBLBCYP11B1CYP11B2MAP3K5 | |
| SCHEMBL24819098 | 0.87 | CBLB (0.43) | CBLBCYP11B1CYP11B2MAP3K5 | |
| SCHEMBL30153100 | 0.86 | CBLB (0.42) | CBLBCETPCYP11B1CYP11B2HPSE | |
| SCHEMBL24820602 | 0.86 | CBLB (0.42) | CBLBCETPCYP11B1CYP11B2HPSE | |
| SCHEMBL24820594 | 0.86 | CBLB (0.42) | CBLBCETPCYP11B1CYP11B2MAP3K5 | |
| SCHEMBL30152718 | 0.86 | CBLB (0.42) | CBLBCETPCYP11B1CYP11B2MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |