Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.46 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792152 | 1.00 | KDM4E (0.49) | KDM4ESLC6A4SLC6A3SMN1; SMN2NPC1 | |
| SCHEMBL31233391 | 0.88 | MAPT (0.43) | KDM4ESLC6A4SLC6A3SMN1; SMN2NPC1 | |
| SCHEMBL29189961 | 0.85 | TSHR (0.52) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL30825433 | 0.84 | CA12 (0.53) | KDM4ESLC6A4SLC6A3SMN1; SMN2NPC1 | |
| SCHEMBL30792061 | 0.82 | EIF4E (0.48) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24820600 | 0.82 | EIF4E (0.48) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24820313 | 0.81 | SLC6A3 (0.65) | KDM4ESLC6A4SLC6A3SMN1; SMN2NPC1 | |
| SCHEMBL24820593 | 0.81 | GRM2 (0.45) | ROCK1CASP1 | |
| SCHEMBL24820114 | 0.80 | KDM4E (0.43) | KDM4ESLC6A4SLC6A3SMN1; SMN2NPC1 | |
| SCHEMBL5120807 | 0.79 | SLC6A3 (0.67) | KDM4ESLC6A4SLC6A3SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637749-A2 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137674-A2 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024086730-A1 | HETEROCYCLIC CBL-B INHIBITORS FOR THE TREATMENT OF CANCER | HOTSPOT THERAPEUTICS, INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |