Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152951 | 1.00 | S1PR1 (0.32) | S1PR1ESR1ESR2 | |
| SCHEMBL30792175 | 0.88 | CLK1 (0.34) | — | |
| SCHEMBL30152710 | 0.88 | CLK1 (0.34) | — | |
| SCHEMBL24820679 | 0.88 | CLK1 (0.34) | — | |
| SCHEMBL30152860 | 0.88 | — | — | |
| SCHEMBL30153071 | 0.87 | CBLB (0.32) | S1PR1ESR1ESR2 | |
| SCHEMBL24819866 | 0.87 | CBLB (0.32) | S1PR1ESR1ESR2 | |
| SCHEMBL24818773 | 0.86 | CD274 (0.33) | — | |
| SCHEMBL30152969 | 0.86 | CD274 (0.33) | — | |
| SCHEMBL24818878 | 0.84 | VSIR (0.40) | S1PR1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |