Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153171 | 1.00 | CASP3 (0.42) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL24818801 | 0.89 | UTRN (0.38) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL30152642 | 0.85 | HPSE (0.56) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL24820110 | 0.84 | KDM4E (0.34) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL30153187 | 0.84 | P2RY14 (0.45) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL24819976 | 0.84 | P2RY14 (0.45) | CASP3SENP7SMN1; SMN2SENP6KDM4E | |
| SCHEMBL30153028 | 0.83 | HPSE (0.46) | SMN1; SMN2LMNAHPSERAB9AP2RY14 | |
| SCHEMBL24819979 | 0.83 | HPSE (0.46) | SMN1; SMN2LMNAHPSERAB9AP2RY14 | |
| SCHEMBL24820727 | 0.82 | FNTA (0.39) | SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL30792055 | 0.82 | FNTA (0.39) | SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |