Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 4/20 | 0.46 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153028 | 1.00 | HPSE (0.46) | HPSEDUSP1TP53LMNAMAPT | |
| SCHEMBL30152642 | 0.91 | HPSE (0.56) | HPSEDUSP1TP53LMNAMAPT | |
| SCHEMBL24818715 | 0.90 | MAPT (0.45) | HPSETP53LMNAMAPTRAB9A | |
| SCHEMBL30792049 | 0.85 | AGPAT2 (0.38) | HPSETP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24820737 | 0.85 | AGPAT2 (0.38) | HPSETP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24820343 | 0.83 | RAB9A (0.46) | HPSETP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30153171 | 0.83 | CASP3 (0.42) | HPSEDUSP1TP53LMNAMAPT | |
| SCHEMBL24820705 | 0.83 | CASP3 (0.42) | HPSEDUSP1TP53LMNAMAPT | |
| SCHEMBL24819976 | 0.83 | P2RY14 (0.45) | HPSETP53LMNAMAPTRAB9A | |
| SCHEMBL30153187 | 0.83 | P2RY14 (0.45) | HPSETP53LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |