Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318476 | 0.85 | FFAR4 (0.53) | MRGPRX4FFAR4SMPD1HDAC1HDAC8 | |
| SCHEMBL6688277 | 0.83 | CTSV (0.54) | HPGDKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL23582396 | 0.81 | MYC (0.48) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4677286 | 0.81 | NPC1 (0.57) | FFAR4HDAC1HDAC6RXRARXRB | |
| SCHEMBL6035274 | 0.80 | CACNA1B (0.55) | MRGPRX4SMPD1KDM4EALDH1A1 | |
| SCHEMBL12295554 | 0.80 | MRGPRX4 (0.68) | MRGPRX4FFAR4RXRARXRBRXRG | |
| SCHEMBL6678156 | 0.79 | RXRA (0.59) | MRGPRX4SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL16189490 | 0.78 | CNR2 (0.54) | KDM4EALDH1A1MAPTCNR1CNR2 | |
| SCHEMBL17024331 | 0.78 | MRGPRX4 (0.55) | MRGPRX4FFAR4RXRARXRBRXRG | |
| SCHEMBL4501862 | 0.78 | HDAC6 (0.57) | MRGPRX4FFAR4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |