Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697264 | 0.87 | MRGPRX4 (0.46) | MRGPRX4MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL12295554 | 0.84 | MRGPRX4 (0.68) | MRGPRX4FFAR4MAPTTDP1L3MBTL1 | |
| SCHEMBL17024333 | 0.83 | RXRA (0.56) | MRGPRX4RXRARXRBRXRGC5AR1 | |
| SCHEMBL20059953 | 0.82 | FFAR4 (0.53) | MRGPRX4FFAR4MAPTTDP1L3MBTL1 | |
| SCHEMBL3980539 | 0.81 | FFAR4 (0.52) | MRGPRX4FFAR4MAPTTDP1L3MBTL1 | |
| SCHEMBL18703359 | 0.80 | MRGPRX4 (0.61) | MRGPRX4FFAR4MAPTTDP1L3MBTL1 | |
| SCHEMBL17024339 | 0.78 | LMNA (0.58) | MAPTL3MBTL1RXRARXRBCYP2C19 | |
| SCHEMBL24820795 | 0.78 | MRGPRX4 (0.57) | MRGPRX4FFAR4MAPTTDP1L3MBTL1 | |
| SCHEMBL1285894 | 0.78 | FFAR4 (0.61) | MRGPRX4FFAR4MAPTTDP1L3MBTL1 | |
| SCHEMBL9631198 | 0.77 | MEN1 (0.53) | MAPTL3MBTL1CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239857-A1 | (THIO)MORPHOLINE DERIVATIVES AS S1P MODULATORS | ABBVIE BAHAMAS LIMITED (BS) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239857-A1 | (THIO)MORPHOLINE DERIVATIVES AS S1P MODULATORS | S1PR3, S1PR1, S1PR2 | MRGPRX4 155/4885FFAR4 457/4885MAPT 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.