Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 12/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24819923 | 1.00 | VSIR (0.42) | VSIRESR1ESR2HPGDHDAC6 | |
| SCHEMBL24821901 | 0.91 | VSIR (0.42) | VSIRESR1ESR2HPGDPDCD1 | |
| SCHEMBL30153065 | 0.91 | VSIR (0.42) | VSIRESR1ESR2HPGDPDCD1 | |
| SCHEMBL24820049 | 0.91 | VSIR (0.42) | VSIRHPGDPDCD1CD274MAPT | |
| SCHEMBL24820720 | 0.90 | VSIR (0.41) | VSIRHPGDPDCD1CD274MAPT | |
| SCHEMBL30153044 | 0.90 | VSIR (0.41) | VSIRHPGDPDCD1CD274MAPT | |
| SCHEMBL24820062 | 0.88 | VSIR (0.40) | VSIRHPGDPDCD1CD274 | |
| SCHEMBL24818674 | 0.88 | VSIR (0.40) | VSIRHPGD | |
| SCHEMBL24818878 | 0.88 | VSIR (0.40) | VSIRESR1ESR2HPGDPDCD1 | |
| SCHEMBL24820156 | 0.88 | VSIR (0.40) | VSIRHPGDPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |