SCHEMBL24822362

SCHEMBL24822362

CN[C@@H](CC(=O)OC(C)(C)C)C(=O)N1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.38
CTSK P43235 4/20 0.36
ITGB3 P05106 6/20 0.35
ITGA2B P08514 6/20 0.35
CYP2D6 P10635 1/20 0.35
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP8 P22894 1/20 0.34
EPHX1 P07099 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23879097 1.00 HPGD (0.38) HPGDCTSKITGB3ITGA2BCYP2D6
SCHEMBL26013230 0.87 HPGD (0.38) HPGDCTSKITGB3ITGA2BCYP2D6
SCHEMBL7298353 0.86 CYP2D6 (0.46) CTSKITGB3ITGA2BCYP2D6CTSL
SCHEMBL23879161 0.86 SMN1; SMN2 (0.49) CTSKCTSLCTSBMEN1CYP3A4
SCHEMBL23893541 0.84 P2RY12 (0.36) HPGDCTSKITGB3ITGA2BCYP2D6
SCHEMBL26010069 0.84 CTSK (0.41) CTSKITGB3ITGA2BCYP2D6CTSL
SCHEMBL14580885 0.83 CTSK (0.38) HPGDCTSKITGB3ITGA2BCYP2D6
SCHEMBL13030795 0.83 CTSK (0.35) HPGDCTSKITGB3ITGA2BCYP2D6
SCHEMBL22044175 0.79 DPP4 (0.41) HPGDCTSKCYP2D6MEN1KMT2A
SCHEMBL15083289 0.78 MMP1 (0.39) HPGDMMP1MMP2MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250257094-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-14 US disclosed
US-12312379-B2 Methods for producing cyclic compounds comprising N-substituted amino acid residues CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-27 US disclosed
US-20240024245-A1 MEDICINE PRODUCTION METHOD INCLUDING STEP OF FREEZE-DRYING WITH MIXED SOLVENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-01-25 US disclosed
US-20240024245-A1 MEDICINE PRODUCTION METHOD INCLUDING STEP OF FREEZE-DRYING WITH MIXED SOLVENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-01-25 US disclosed
US-20240024245-A1 MEDICINE PRODUCTION METHOD INCLUDING STEP OF FREEZE-DRYING WITH MIXED SOLVENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-01-25 US disclosed
EP-4248951-A1 MEDICINE PRODUCTION METHOD INCLUDING STEP OF FREEZE-DRYING WITH MIXED SOLVENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-27 EP disclosed
US-20220411462-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-12-29 US disclosed
US-20220411462-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-12-29 US disclosed
WO-2022234864-A1 METHOD FOR PRODUCING CYCLIC COMPOUND CONTAINING N-SUBSTITUTED AMINO ACID RESIDUE 中外製薬株式会社 2022-11-10 WO disclosed
EP-4086272-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411462-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES NGLY1, NPPA, VIP HPGD 1470/4885CTSK 3284/4885ITGB3 4867/4885
US-12312379-B2 Methods for producing cyclic compounds comprising N-substituted amino acid residues NGLY1, NPPA, VIP HPGD 1470/4885CTSK 3284/4885ITGB3 4867/4885
US-20240024245-A1 MEDICINE PRODUCTION METHOD INCLUDING STEP OF FREEZE-DRYING WITH MIXED SOLVENT NEFM, CMA1, CYP2W1 HPGD 887/4885CTSK 1090/4885ITGB3 4747/4885
US-20250257094-A1 METHODS FOR PRODUCING CYCLIC COMPOUNDS COMPRISING N-SUBSTITUTED AMINO ACID RESIDUES NGLY1, NPPA, VIP HPGD 1470/4885CTSK 3284/4885ITGB3 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.