Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22498528 | 0.76 | ALDH1A1 (0.41) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL29656885 | 0.76 | ALDH1A1 (0.41) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL277948 | 0.72 | PDE3B (0.45) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL22510361 | 0.71 | MAPT (0.33) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL29659903 | 0.71 | MAPT (0.33) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL22498617 | 0.70 | ALDH1A1 (0.32) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL22498586 | 0.70 | MAPT (0.33) | PDE3BPDE3A | |
| SCHEMBL31588422 | 0.70 | MAPT (0.33) | PDE3BPDE3A | |
| SCHEMBL29659859 | 0.70 | ALDH1A1 (0.32) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL29208860 | 0.69 | PDE3B (0.34) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294517-A1 | 2-[3-[1 [(QUINAZOLIN-4-YL)AMINO]ETHYL]PYRAZIN-2-YL]THIAZOLE-5-CARBONITRILE DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2024-09-05 | — | — | US | disclosed |
| CN-117561252-A | 2- [3- [1[ (quinazolin-4-yl) amino ] ethyl ] pyrazin-2-yl ] thiazole-5-carbonitrile derivatives and similar compounds as pesticides | 先正达农作物保护股份公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2022268648-A1 | 2-[3-[1 [(QUINAZOLIN-4-YL)AMINO]ETHYL]PYRAZIN-2-YL]THIAZOLE-5-CARBONITRILE DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294517-A1 | 2-[3-[1 [(QUINAZOLIN-4-YL)AMINO]ETHYL]PYRAZIN-2-YL]THIAZOLE-5-CARBONITRILE DERIVATIVES AND SIMILAR COMPOUNDS AS PESTICIDES | ACHE, CHRM5, API5 | ALDH1A1 406/4885PDE3B 423/4885PDE3A 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.