Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29656885 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL25780878 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4ETDP1KMT2AMAPT | |
| SCHEMBL22510361 | 0.82 | MAPT (0.33) | ALDH1A1KDM4ETDP1KMT2APDE3B | |
| SCHEMBL29659903 | 0.82 | MAPT (0.33) | ALDH1A1KDM4ETDP1KMT2APDE3B | |
| SCHEMBL31588422 | 0.81 | MAPT (0.33) | KDM4EPDE3BPDE3ARAB9ANPC1 | |
| SCHEMBL22498586 | 0.81 | MAPT (0.33) | KDM4EPDE3BPDE3ARAB9ANPC1 | |
| SCHEMBL29659859 | 0.81 | ALDH1A1 (0.32) | ALDH1A1KDM4EMEN1KMT2APDE3B | |
| SCHEMBL22498617 | 0.81 | ALDH1A1 (0.32) | ALDH1A1KDM4EMEN1KMT2APDE3B | |
| SCHEMBL277948 | 0.79 | PDE3B (0.45) | ALDH1A1KDM4EKMT2APDE3BPDE3A | |
| SCHEMBL25780702 | 0.79 | L3MBTL1 (0.51) | ALDH1A1KDM4ETDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12527325-B2 | Pesticidally active diazine-amide compounds | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-20 | — | — | US | disclosed |
| EP-4643644-A2 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-11-05 | — | — | EP | disclosed |
| EP-4051673-B1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-09-24 | — | — | EP | disclosed |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20230002359-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-05 | — | — | US | disclosed |
| US-20230002359-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-05 | — | — | US | disclosed |
| EP-4051673-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-09-07 | — | — | EP | disclosed |
| US-20220159958-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-26 | — | — | US | disclosed |
| US-20220159958-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-26 | — | — | US | disclosed |
| EP-3947359-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-02-09 | — | — | EP | disclosed |
| WO-2021083936-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-05-06 | — | — | WO | disclosed |
| WO-2021083936-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-05-06 | — | — | WO | disclosed |
| WO-2020201398-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-08 | — | — | WO | disclosed |
| WO-2020201398-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527325-B2 | Pesticidally active diazine-amide compounds | DDT, CHRM1, C3AR1 | ALDH1A1 1101/4885KDM4E 2846/4885TDP1 2781/4885 |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, GSTO1 | ALDH1A1 922/4885KDM4E 3772/4885TDP1 1201/4885 |
| US-20230002359-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, GSTO1 | ALDH1A1 746/4885KDM4E 3629/4885TDP1 1292/4885 |
| US-20220159958-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | ALDH1A1 1304/4885KDM4E 2665/4885TDP1 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.