SCHEMBL248231

SCHEMBL248231

CO/C=C(/C(=O)OC)c1ccccc1Oc1cc(Oc2ccccc2NS)ncn1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPK8 P45983 1/20 0.36
MAPK10 P53779 1/20 0.36
NPSR1 Q6W5P4 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RAB9A P51151 1/20 0.33
PTK2 Q05397 1/20 0.32
CCR2 P41597 1/20 0.32
CYP3A4 P08684 1/20 0.31
MAP2K7 O14733 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363262 0.92 KMT2A (0.36) MEN1KMT2AMAPK8MAPK10NPSR1
SCHEMBL2873428 0.92 KMT2A (0.36) MEN1KMT2AMAPK8MAPK10NPSR1
SCHEMBL16561719 0.91 MEN1 (0.41) MEN1KMT2AMAPK8MAPK10NPSR1
SCHEMBL6744761 0.90 RAB9A (0.36) MEN1KMT2AMAPK8MAPK10ALDH1A1
SCHEMBL10431041 0.90 RAB9A (0.36) MEN1KMT2AMAPK8MAPK10ALDH1A1
SCHEMBL6748555 0.88 TSHR (0.40) MEN1KMT2AMAPK8MAPK10NPSR1
SCHEMBL9281283 0.87 NPC1 (0.33) MAPK8MAPK10NPSR1RAB9A
SCHEMBL29361759 0.87 MEN1 (0.37) MEN1KMT2AMAPK8MAPK10NPSR1
SCHEMBL28928885 0.87 MEN1 (0.37) MEN1KMT2AMAPK8MAPK10NPSR1
SCHEMBL9121807 0.87 HTT (0.44) MEN1KMT2AMAPK8MAPK10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430980-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-09-02 CN disclosed
CN-109071520-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-06-14 CN disclosed
CN-111093372-B Microbicidal quinoline (thio) carboxamide derivatives 先正达参股股份有限公司 2022-05-27 CN disclosed
CN-111050558-B Microbicidal quinoline (thio) carboxamide derivatives 先正达参股股份有限公司 2022-05-27 CN disclosed
CN-108137517-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-04-12 CN disclosed
CN-109071522-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-04-12 CN disclosed
CN-108779109-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-03-11 CN disclosed
CN-108137570-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 CN disclosed
CN-113873886-A Overcoat compositions 特洛伊公司 2021-12-31 CN disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
US-6197799-B1 PLANT SAFENING AGENTS; PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed
US-5990043-A COMPRISES AT LEAST ONE INSECTICIDE SELECTED FROM TRIFLUMURON, FLUFENOXURON, FLUCYCLOXURON, HEXAFLUMURON, AND OTHERS; A CARRIER AND BINDER; PROTECTS ITEMS SUCH AS SHIP HULLS IN BRACKISH OR SEAWATER FROM BARNICLE INFESTATIONS BAYER AKTIENGESELLSCHAFT (DE) 1999-11-23 US disclosed
US-5972971-A WOOD PRESERVATIVE CONSISTS OF A MIXTURE OF METACONAZOLE OR AN ACID ADDITION SALT OR METAL COMPLEX AND IMIDACLOPRID OR SALT OR METAL COMPLEX BAYER AKTIENGESELLSCHAFT (DE) 1999-10-26 US disclosed
EP-0750542-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AG (DE) 1997-01-02 EP disclosed
EP-0713485-A1 THIOCARBAMOYL COMPOUNDS BAYER AG (DE) 1996-05-29 EP disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 WO disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 WO disclosed
WO-1995004722-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1995-02-16 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 MEN1 2747/4885KMT2A 1539/4885MAPK8 4031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.