⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30310958 | 1.00 | — | — | |
| SCHEMBL24823322 | 0.86 | RXFP1 (0.38) | — | |
| SCHEMBL30311034 | 0.86 | RXFP1 (0.38) | — | |
| SCHEMBL24823318 | 0.77 | DYRK1A (0.37) | — | |
| SCHEMBL30310938 | 0.77 | DYRK1A (0.37) | — | |
| SCHEMBL24823317 | 0.77 | DYRK1A (0.37) | — | |
| SCHEMBL30310926 | 0.77 | DYRK1A (0.37) | — | |
| SCHEMBL30952889 | 0.76 | RAB9A (0.37) | — | |
| SCHEMBL23625903 | 0.76 | RAB9A (0.37) | — | |
| SCHEMBL30952890 | 0.74 | SMN1; SMN2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843293-A | Tricyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-03-24 | — | — | CN | disclosed |
| WO-2022267930-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2022-12-29 | — | — | WO | disclosed |