Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2482352

CC1=C([Zr+2]c2cccc3c2Cc2ccccc2-3)CC=C1.[Cl-].[Cl-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
PGR P06401 1/20 0.33
HTR7 P34969 1/20 0.32
HTR2B P41595 1/20 0.32
MAP3K9 P80192 1/20 0.31
MAP3K11 Q16584 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7553221 0.83 PNMT (0.38) PNMTNPC1RAB9ADRD2DRD4
Hydrochloric Acid SCHEMBL7549761 0.79 MAPT (0.39) NPC1RAB9ADRD2DRD3MAP3K9
Hydrochloric Acid SCHEMBL7752720 0.79 PNMT (0.35) PNMTNPC1RAB9ADRD2DRD4
Hydrochloric Acid SCHEMBL29479988 0.79 PNMT (0.50) PNMTNPC1RAB9ADRD2DRD4
Hydrochloric Acid SCHEMBL618215 0.79 PNMT (0.50) PNMTNPC1RAB9ADRD2DRD4
Iodide SCHEMBL7930583 0.79 PNMT (0.36) PNMTNPC1RAB9ADRD2DRD4
Hydrochloric Acid SCHEMBL6445067 0.79 PNMT (0.36) PNMTNPC1RAB9ADRD2DRD4
Hydrochloric Acid SCHEMBL7553835 0.78 PNMT (0.37) PNMTNPC1RAB9ADRD2DRD4
Hydrochloric Acid SCHEMBL10513406 0.77 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
Hydrochloric Acid SCHEMBL6471201 0.77 PNMT (0.35) PNMTNPC1RAB9ADRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12152101-B2 Process for preparing catalysts and catalyst compositions FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2024-11-26 US disclosed
US-20240084051-A1 PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2024-03-14 US disclosed
US-11814461-B2 Process for preparing catalysts and catalyst compositions FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2023-11-14 US disclosed
US-20230242683-A1 PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2023-08-03 US disclosed
US-11634513-B2 Process for preparing catalysts and catalyst compositions FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2023-04-25 US disclosed
EP-4097153-A1 PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS Formosa Plastics Corporation, U.S.A. (US) 2022-12-07 EP disclosed
US-20220242976-A1 PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2022-08-04 US disclosed
US-11339229-B2 Process for preparing catalysts and catalyst compositions FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2022-05-24 US disclosed
WO-2021154204-A1 PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2021-08-05 WO disclosed
US-20210230318-A1 PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2021-07-29 US disclosed
EP-2059538-B1 PROCESS FOR REMOVAL OF RESIDUAL CATALYST COMPONENTS CHEMTURA CORP (US) 2011-10-19 EP disclosed
US-7601255-B2 Process for removal of residual catalyst components CHEMTURA CORPORATION (US) 2009-10-13 US disclosed
EP-2059538-A2 PROCESS FOR REMOVAL OF RESIDUAL CATALYST COMPONENTS Chemtura Corporation (US) 2009-05-20 EP disclosed
WO-2008030387-A2 PROCESS FOR REMOVAL OF RESIDUAL CATALYST COMPONENTS CHEMTURA CORPORATION (US) 2008-03-13 WO disclosed
US-20080053873-A1 Process for removal of residual catalyst components LANXESS SOLUTIONS US INC. 2008-03-06 US disclosed
EP-0841349-B1 Catalyst for alpha-olefin polymerization and production of poly-alpha-olefin therewith MITSUI CHEMICALS INC (JP) 2002-06-12 EP disclosed
US-6121394-A Metallocene-catalyzed olefin polymerization in the absence of aluminoxane MITSUI CHEMICALS, INC. (JP) 2000-09-19 US disclosed
EP-0500944-B1 CATALYST FOR ALPHA-OLEFIN POLYMERIZATION AND PRODUCTION OF POLY-ALPHA-OLEFIN THEREWITH MITSUI CHEMICALS INC (JP) 1998-10-07 EP disclosed
EP-0841349-A2 Catalyst for alpha-olefin polymerization and production of poly-alpha-olefin therewith MITSUI TOATSU CHEMICALS, Inc. (JP) 1998-05-13 EP disclosed
EP-0500944-A1 CATALYST FOR $g(a)-OLEFIN POLYMERIZATION AND PRODUCTION OF POLY-$g(a)-OLEFIN THEREWITH MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-02 EP disclosed