Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24826477 | 0.83 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL14268235 | 0.74 | PARP1 (0.31) | — | |
| SCHEMBL24817956 | 0.72 | KCNH2 (0.34) | — | |
| SCHEMBL13036606 | 0.72 | TDP1 (0.40) | CSF1RCDK4CDK6 | |
| SCHEMBL27358232 | 0.72 | PTPN2 (0.41) | — | |
| SCHEMBL23774654 | 0.71 | OGA (0.44) | RIPK1 | |
| SCHEMBL3353090 | 0.69 | HTR4 (0.33) | RIPK1 | |
| SCHEMBL26005534 | 0.68 | PTGS1 (0.37) | — | |
| SCHEMBL25081424 | 0.68 | RIPK1 (0.53) | RIPK1 | |
| SCHEMBL18252802 | 0.66 | TMEM97 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |