Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353090 | 0.83 | HTR4 (0.33) | RIPK1TMEM97SIGMAR1KCNH2 | |
| SCHEMBL24823633 | 0.83 | CSF1R (0.36) | RIPK1 | |
| SCHEMBL24824864 | 0.81 | PNMT (0.34) | RIPK1SIGMAR1KCNH2 | |
| SCHEMBL2989704 | 0.79 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL24823540 | 0.78 | PTGER2 (0.32) | RIPK1 | |
| SCHEMBL2991734 | 0.77 | NOTUM (0.43) | RIPK1TMEM97SIGMAR1KCNH2 | |
| SCHEMBL12407085 | 0.74 | NOTUM (0.44) | — | |
| SCHEMBL24823595 | 0.72 | ASIC3 (0.30) | — | |
| SCHEMBL4949018 | 0.72 | ALDH1A1 (0.37) | — | |
| SCHEMBL24824515 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |