Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | S100A9 | P06702 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.30 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1641567 | 0.77 | ENPP2 (0.37) | ENPP2PTGS2LOXL2LOX | |
| SCHEMBL13241045 | 0.75 | ENPP2 (0.36) | ENPP2PTGS2LOXL2LOX | |
| SCHEMBL12614860 | 0.75 | ENPP2 (0.46) | ENPP2PTGS2LOXL2LOXS100A9 | |
| SCHEMBL27352424 | 0.75 | PTGS2 (0.39) | ENPP2PTGS2 | |
| SCHEMBL1641672 | 0.75 | TP53 (0.42) | ENPP2LOXL2LOXKDM4EFYN | |
| SCHEMBL1641639 | 0.75 | SMN1; SMN2 (0.37) | ENPP2PTGS2S100A9 | |
| SCHEMBL3599742 | 0.75 | ENPP2 (0.41) | ENPP2PTGS2LOXL2LOXKDM4E | |
| SCHEMBL24714798 | 0.71 | MAPT (0.34) | ENPP2PTGS2LOXL2LOXS100A9 | |
| SCHEMBL1688250 | 0.71 | LRRK2 (0.41) | ENPP2MAP4K4 | |
| SCHEMBL23314218 | 0.71 | ALDH1A1 (0.33) | ENPP2PTGS2LOXL2LOXMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |