SCHEMBL2482630

SCHEMBL2482630

CC(C)c1cc(C(=O)CI)cc(C(C)C)c1O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.51
GABRB1 P18505 4/20 0.51
GABRB2 P47870 1/20 0.50
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
GLRA1 P23415 2/20 0.46
GAA P10253 4/20 0.46
GSR P00390 1/20 0.43
HTT P42858 2/20 0.42
LMNA P02545 1/20 0.42
ALDH1A1 P00352 1/20 0.42
BCL2 P10415 1/20 0.40
MCL1 Q07820 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12205439 0.84 PPARA (0.45) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL27584559 0.82 GABRA1 (0.53) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL2484139 0.81 GABRA1 (0.51) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL2485093 0.81 GABRA1 (0.51) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL21660797 0.79 GABRA1 (0.50) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL28078271 0.77 GABRA1 (0.78) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL27262232 0.77 GAA (0.57) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL25760150 0.77 GABRA1 (0.47) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL4319072 0.75 GABRA1 (0.63) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL2341096 0.75 GABRA1 (0.58) GABRA1GABRB1GABRB2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945705-B1 PHOTOLATENT SYSTEMS BASF SE (DE) 2011-10-19 EP disclosed
US-7820865-B2 Photolatent systems CIBA CORPORATION (US) 2010-10-26 US disclosed
US-7820865-B2 Photolatent systems CIBA CORPORATION (US) 2010-10-26 US disclosed
US-20090162307-A1 Photolatent Systems CIBA CORP. 2009-06-25 US disclosed
US-20090162307-A1 Photolatent Systems CIBA CORP. 2009-06-25 US disclosed
EP-1945705-A1 PHOTOLATENT SYSTEMS Ciba Holding Inc. (CH) 2008-07-23 EP disclosed
WO-2007054446-A1 PHOTOLATENT SYSTEMS CIBA HOLDING INC. (CH) 2007-05-18 WO disclosed
EP-1223933-A2 5-MEMBERED HETEROCYCLE DERIVATIVES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2002-07-24 EP disclosed
WO-2001026656-A2 5-MEMBERED HETEROCYCLE DERIVATIVES AND USE THEREOF AS MONOAMINE OXIDASE INHIBITORS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2001-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090162307-A1 Photolatent Systems CCNT1, CCNT2, C1S GABRA1 3210/4885GABRB1 3049/4885GABRB2 3331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.