SCHEMBL4319072

SCHEMBL4319072

CC(C)c1cc(C(=O)O)cc(C(C)C)c1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.63
GABRB1 P18505 4/20 0.63
THRA P10827 1/20 0.60
THRB P10828 1/20 0.60
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
GABRB2 P47870 1/20 0.52
GAA P10253 3/20 0.52
LMNA P02545 2/20 0.51
HTT P42858 1/20 0.51
GLRA1 P23415 1/20 0.51
ALDH1A1 P00352 2/20 0.50
CA12 O43570 2/20 0.50
CA3 P07451 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl Alcohol SCHEMBL28142316 0.96 GABRA1 (0.59) GABRA1GABRB1THRATHRBCA1
SCHEMBL15524731 0.90 CA1 (0.61) GABRA1GABRB1THRATHRBCA1
SCHEMBL22005119 0.88 GABRA1 (0.51) GABRA1GABRB1THRATHRBCA1
SCHEMBL22004162 0.86 TTR (0.64) GABRA1GABRB1THRATHRBCA1
SCHEMBL14273021 0.85 GABRA1 (0.49) GABRA1GABRB1THRATHRBCA1
SCHEMBL28260303 0.84 GABRA1 (0.49) GABRA1GABRB1THRATHRBCA1
SCHEMBL28260301 0.84 GABRA1 (0.49) GABRA1GABRB1THRATHRBCA1
SCHEMBL28078271 0.84 GABRA1 (0.78) GABRA1GABRB1CA1CA2GABRB2
SCHEMBL10554155 0.83 GLRA3 (0.50) GABRA1GABRB1THRATHRBCA1
Acetic Acid SCHEMBL1928603 0.83 GABRA1 (0.59) GABRA1GABRB1THRATHRBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250059116-A1 PROCESS FOR PRODUCING PROPOFOL PCAS (FR) 2025-02-20 US claimed
WO-2023111488-A1 PROCESS FOR PRODUCING PROPOFOL PCAS (FR) 2023-06-22 WO claimed
US-20230174444-A1 PROCESS FOR THE PREPARATION OF PROPOFOL FRESENIUS KABI ONCOLOGY LTD. (IN) 2023-06-08 US claimed
EP-4126803-A1 PROCESS FOR THE PREPARATION OF PROPOFOL Fresenius Kabi Oncology Limited (IN) 2023-02-08 EP claimed
WO-2021191832-A1 PROCESS FOR THE PREPARATION OF PROPOFOL FRESENIUS KABI ONCOLOGY LTD. (IN) 2021-09-30 WO claimed
EP-2516369-B1 PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL HARMAN FINOCHEM LTD (IN) 2015-07-22 EP claimed
US-8664452-B2 Process for preparing extra pure 2, 6-diisopropyl phenol HARMAN FINOCHEM LIMITED (US) 2014-03-04 US claimed
US-20130072573-A1 PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL HARMAN FINOCHEM LIMITED (IN) 2013-03-21 US claimed
EP-2516369-A1 PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL Harman Finochem Limited (IN) 2012-10-31 EP claimed
WO-2011161687-A1 PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL HARMAN FINOCHEM LIMITED (IN) 2011-12-29 WO claimed
US-5702887-A BENZ(B)ACRIDINIUM-12-CARBOXYLATE COMPOUNDS CHIRON DIAGNOSTICS CORPORATION (US) 1997-12-30 US claimed
US-20250059116-A1 PROCESS FOR PRODUCING PROPOFOL PCAS (FR) 2025-02-20 US disclosed
US-20250059116-A1 PROCESS FOR PRODUCING PROPOFOL PCAS (FR) 2025-02-20 US disclosed
EP-4448475-A1 PROCESS FOR PRODUCING PROPOFOL PCAS (FR) 2024-10-23 EP disclosed
WO-2024186986-A1 SELF-OPTIMIZING REGRESSION MODEL VIRGINIA COMMONWEALTH UNIVERSITY (US) 2024-09-12 WO disclosed
US-4255304-A DISCOLORATION INHIBITION AMERICAN CYANAMID COMPANY (US) 1981-03-10 US disclosed
US-4248594-A PRINTING, DYEING NICKEL SALTS OF 4-HYDROXYBENZOIC ACIDS AMERICAN CYANAMID COMPANY (US) 1981-02-03 US disclosed
US-4144029-A PREPARED BY REACTION OF A NICKEL P-HYDROXYBENZOATE WITH AN ORGANIC PHOSPHITE AMERICAN CYANAMID COMPANY (US) 1979-03-13 US disclosed
US-4072707-A Preparation of 3,5-dialkyl-4-hydroxybenzoic acid AMERICAN CYANAMID COMPANY (US) 1978-02-07 US disclosed
US-4011196-A STABILIZED POLYESTER RESIN AND PROCESSES FOR MAKING THEM FMC CORPORATION (US) 1977-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174444-A1 PROCESS FOR THE PREPARATION OF PROPOFOL CYP3A4, CYP3A5, GABARAPL1 GABRA1 18/4885GABRB1 31/4885THRA 1882/4885
US-20130072573-A1 PROCESS FOR PREPARING EXTRA PURE 2, 6-DIISOPROPYL PHENOL CYP2B6, CYP2D6, CYP2A6 GABRA1 133/4885GABRB1 200/4885THRA 2608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.