SCHEMBL2482646

SCHEMBL2482646

CCOC(=O)CNC(=O)OCC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.59
MGAM O43451 1/20 0.56
SI P14410 1/20 0.56
MGAM2 Q2M2H8 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.47
PPID Q08752 2/20 0.47
ALDH1A1 P00352 6/20 0.46
TRPA1 O75762 1/20 0.46
TSHR P16473 1/20 0.46
MAPT P10636 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HPGD P15428 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PPIB P23284 1/20 0.45
PPIA P62937 1/20 0.45
PPIG Q13427 1/20 0.45
EPHX2 P34913 1/20 0.44
EGLN1 Q9GZT9 1/20 0.42
NLRP3 Q96P20 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27762950 0.98 GAA (0.57) GAAMGAMSIMGAM2SMN1; SMN2
SCHEMBL9404556 0.88 GAA (0.57) GAAMGAMSIMGAM2SMN1; SMN2
SCHEMBL11184401 0.88 ALDH1A1 (0.56) GAAMGAMSIMGAM2SMN1; SMN2
SCHEMBL2183329 0.87 GAA (0.52) GAAMGAMSIMGAM2SMN1; SMN2
SCHEMBL9374452 0.84 ACHE (0.55) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL10087936 0.84 SMN1; SMN2 (0.50) GAAMGAMSIMGAM2SMN1; SMN2
SCHEMBL3424560 0.84 ACHE (0.50) GAASMN1; SMN2ALDH1A1
SCHEMBL7946756 0.83 PPID (0.62) GAAMGAMSIMGAM2SMN1; SMN2
SCHEMBL7089973 0.83 GAA (0.61) GAAMGAMSIMGAM2SMN1; SMN2
SCHEMBL1936376 0.83 ALDH1A1 (0.52) GAAMGAMSIMGAM2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110484190-B Solvent-free single-component moisture-curing polyurethane adhesive for caravan bodies and preparation method thereof 山西省应用化学研究所(有限公司) 2021-05-18 CN claimed
CN-104893604-B Transparent thermal-insulation window film 浙江省能源与核技术应用研究院 2017-04-12 CN claimed
CN-104893604-A Transparent thermal-insulation window film ZHEJIANG ENERGY AND NUCLEAR TECHNOLOGY APPLIC RES INST 2015-09-09 CN claimed
CN-114369052-B Synthesis method of 3-aminopyrrolidine dihydrochloride 赤峰万泽药业股份有限公司 2024-10-15 CN disclosed
CN-118755684-A Catalytic enzyme for producing chiral aromatic amine, N-heterocyclic amine and derivatives thereof with high optical purity, and preparation method and application thereof 杭州微远生物科技有限公司 2024-10-11 CN disclosed
CN-111592480-B Preparation method of cefpiramate intermediate (R) -1-tert-butoxycarbonyl-3-aminopyrrolidine 山西千岫制药有限公司 2023-06-23 CN disclosed
CN-115974747-A Preparation method and application of 3- (3-chloropropyl) -4-oxopyrrolidine-1-carboxylic acid ethyl ester 上海北卡医药技术有限公司 2023-04-18 CN disclosed
CN-110746334-B Method for preparing 3- (3-chloropropyl) -4-oxopyrrolidine-1-carboxylic ester 上海朴颐化学科技有限公司 2023-03-14 CN disclosed
CN-109111719-B Wave-absorbing material and preparation method thereof 洛阳尖端技术研究院 2022-12-13 CN disclosed
CN-114369052-A Synthetic method of 3-aminopyrrolidine dihydrochloride 赤峰万泽药业股份有限公司 2022-04-19 CN disclosed
CN-214362671-U Anti-icing highway pavement structure 河南未来交通科技有限公司 2021-10-08 CN disclosed
EP-1904547-A1 POLYURETHANES DERIVED FROM OLIGOMERIC FLUOROACRYLATES 3M Innovative Properties Company (US) 2008-04-02 EP disclosed
CN-1331852-C Synthesis method of N-substituted-3-amidopyrrolidine and its bihydrochlorate UNIV ZHEJIANG (CN) 2007-08-15 CN disclosed
WO-2007002894-A1 POLYURETHANES DERIVED FROM OLIGOMERIC FLUOROACRYLATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-01-04 WO disclosed
US-20070004895-A1 Polyurethanes derived from oligomeric fluoroacrylates 3M INNOVATIVE PROPERTIES COMPANY 2007-01-04 US disclosed
CN-1733720-A Synthesis method of N-substituted-3-amidopyrrolidine and its bihydrochlorate UNIV ZHEJIANG (CN) 2006-02-15 CN disclosed
US-5928933-A SEPARATING RACEMIC MIXTURE BY ENANTIOSELECTIVELY HYDROLYZING THE ESTER OF THE L-ISOMER; CHEMICAL INTERMEDIATE FOR 4-HYDROXYPROLINE E. I. DU PONT DE NEMOURS & COMPANY (US) 1999-07-27 US disclosed
US-4515731-A Asymmetric catalysis MONSANTO COMPANY (US) 1985-05-07 US disclosed
US-4421693-A INSECTICIDES, MITICIDES OR NEMATOCIDES OTSUKA CHEMICAL CO., LTD. (JP) 1983-12-20 US disclosed
US-4413005-A 2,3-DIHYDRO-2,2-DIMETHYLBENZOFURAN-7-YL DERIVATIVES OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1983-11-01 US disclosed