Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.69 |
| ▸ | PGR | P06401 | 6/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | AR | P10275 | 3/20 | 0.64 |
| ▸ | F2 | P00734 | 1/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | IL6 | P05231 | 1/20 | 0.49 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | GLUL | P15104 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602408 | 0.91 | CYP3A4 (0.72) | CYP3A4HIF1ANR3C1PGRHSD17B10 | |
| SCHEMBL6835391 | 0.91 | CYP3A4 (0.72) | CYP3A4HIF1ANR3C1PGRHSD17B10 | |
| SCHEMBL21145516 | 0.88 | CYP3A4 (0.78) | CYP3A4HIF1ANR3C1PGRHSD17B10 | |
| SCHEMBL10798815 | 0.86 | CYP3A4 (0.74) | CYP3A4HIF1ANR3C1PGRHSD17B10 | |
| SCHEMBL10798820 | 0.86 | CYP3A4 (0.74) | CYP3A4HIF1ANR3C1PGRHSD17B10 | |
| SCHEMBL9789817 | 0.85 | NR3C1 (0.69) | CYP3A4HIF1ANR3C1PGRHSD17B10 | |
| SCHEMBL5299558 | 0.85 | NR3C1 (0.68) | CYP3A4HIF1ANR3C1PGRHSD17B10 | |
| SCHEMBL11503763 | 0.85 | NR3C1 (0.68) | CYP3A4HIF1ANR3C1PGRHSD17B10 | |
| SCHEMBL27737031 | 0.85 | NR3C1 (0.67) | CYP3A4HIF1ANR3C1PGRHSD17B10 | |
| SCHEMBL3406702 | 0.84 | CYP3A4 (0.81) | CYP3A4HIF1ANR3C1PGRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108366-B1 | Idebenone for the treatment of respiratory illness in muscular dystrophy | SANTHERA PHARMACEUTICALS CH (CH) | 2011-10-19 | — | — | EP | claimed |