Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Trolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL4654746 | 1.00 | CA5A (0.40) | CA5ACA5BMAPTSMN1; SMN2KDM4E | |
| Trolamine SCHEMBL3843888 | 1.00 | CA5A (0.40) | CA5ACA5BMAPTSMN1; SMN2KDM4E | |
| Trolamine SCHEMBL28081685 | 0.97 | CA5A (0.38) | CA5ACA5BMAPTSMN1; SMN2KDM4E | |
| Trolamine SCHEMBL8619061 | 0.97 | CA5A (0.38) | CA5ACA5BMAPTSMN1; SMN2KDM4E | |
| Trolamine SCHEMBL28711400 | 0.91 | MAPT (0.36) | CA5ACA5BMAPTSMN1; SMN2KDM4E | |
| Trolamine SCHEMBL28711399 | 0.91 | MAPT (0.36) | CA5ACA5BMAPTSMN1; SMN2KDM4E | |
| Trolamine SCHEMBL11574269 | 0.91 | MAPT (0.34) | CA5ACA5BMAPTSMN1; SMN2KDM4E | |
| Sulfuric Acid SCHEMBL28902821 | 0.89 | NPSR1 (0.35) | CA5ACA5BMAPTSMN1; SMN2KDM4E | |
| Trolamine SCHEMBL28225633 | 0.89 | SMN1; SMN2 (0.43) | CA5ACA5BMAPTSMN1; SMN2KDM4E | |
| Trolamine SCHEMBL9827519 | 0.88 | MAPT (0.38) | MAPTSMN1; SMN2KDM4EALOX15NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 735 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899359-A | Conductive high-molecular monomer composition, conductive polymer and electrolytic capacitor | 深圳新宙邦科技股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119899592-A | Silicon dioxide polishing solution and preparation method thereof | 甬江实验室 | 2025-04-29 | — | — | CN | claimed |
| CN-119799406-A | High-cooling-performance water-based semisynthetic cutting fluid and application thereof | 厦门理工学院 | 2025-04-11 | — | — | CN | claimed |
| CN-119752522-A | High-stability aqueous emulsion and preparation method thereof | 厦门理工学院 | 2025-04-04 | — | — | CN | claimed |
| CN-116334626-B | W etching solution with controllable side etching relative to laminated metal and preparation method thereof | 湖北兴福电子材料股份有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-111466376-B | Multifunctional agricultural adjuvant composition | 温菲尔德解决方案公司 | 2025-01-07 | — | — | CN | claimed |
| CN-119265740-A | Preparation method of regenerated colored polyester fiber | 江苏轩达高分子材料有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-117695808-B | VOC (volatile organic compound) treating agent and preparation method thereof | 山东联化新材料有限责任公司 | 2024-10-25 | — | — | CN | claimed |
| CN-117603613-B | Vehicle chassis antirust agent and preparation method thereof | 泰伦特生物工程股份有限公司 | 2024-05-31 | — | — | CN | claimed |
| US-20240114901-A1 | MULTIFUNCTIONAL AGRICULTURAL ADJUVANT COMPOSITIONS | WINFIELD SOLUTIONS, LLC | 2024-04-11 | — | — | US | claimed |
| CN-102303125-A | Method for preparing nano silver powder in viscous medium | UNIV NANJING FORESTRY | 2012-01-04 | — | — | CN | claimed |
| CN-102274979-A | Method for preparing nano copper powder in micromolecular viscous medium | — | 2011-12-14 | — | — | CN | claimed |
| CN-101767021-B | Method for preparing p-CoO/n-CdS compound semiconductor photocatalyst | UNIV NANJING FORESTRY | 2011-09-07 | — | — | CN | claimed |
| CN-102125858-A | Preparation method of p-CuO/n-CdS/ZnS composite semiconductor photochemical catalyst | UNIV NANJING FORESTRY | 2011-07-20 | — | — | CN | claimed |
| CN-102085482-A | Preparation method of p-CoO/n-CdS/TiO2 composite semiconductor photocatalyst | UNIV NANJING FORESTRY | 2011-06-08 | — | — | CN | claimed |
| CN-101767021-A | Method for preparing p-CoO/n-CdS compound semiconductor photocatalyst | UNIV NANJING FORESTRY | 2010-07-07 | — | — | CN | claimed |
| US-20030038085-A1 | Methods for lowering pH in leather processing solutions | SARGENT R RICHARD (US) | 2003-02-27 | — | — | US | claimed |
| CN-1330901-A | Health-care handbag for woman | FUJIAN ENTPR CO LTD GUANGDONG (CN) | 2002-01-16 | — | — | CN | claimed |
| US-20010045393-A1 | METHOD FOR LOWERING PH IN LEATHER PROCESSING SOLUTIONS | PEACH STATE LABS, INC. | 2001-11-29 | — | — | US | claimed |
| US-5773397-A | Bubble bath composition | KAO CORPORATION (JP) | 1998-06-30 | — | — | US | claimed |