Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482828 | 1.00 | RAB9A (0.43) | RAB9AHPGDL3MBTL1GAAPOLB | |
| SCHEMBL2482831 | 1.00 | RAB9A (0.43) | RAB9AHPGDL3MBTL1GAAPOLB | |
| SCHEMBL17074314 | 0.94 | SLC6A3 (0.45) | RAB9AHPGDL3MBTL1GAAPOLB | |
| SCHEMBL536802 | 0.81 | HPGD (0.39) | RAB9AHPGDL3MBTL1GAAPOLB | |
| SCHEMBL18281723 | 0.80 | HPGD (0.40) | RAB9AHPGDL3MBTL1GAAPOLB | |
| SCHEMBL17870819 | 0.80 | HPGD (0.40) | RAB9AHPGDL3MBTL1GAAPOLB | |
| SCHEMBL11851506 | 0.78 | MEN1 (0.41) | RAB9AHPGDL3MBTL1GAAPOLB | |
| Acetic Acid SCHEMBL7279012 | 0.78 | RAB9A (0.39) | RAB9AHPGDL3MBTL1GAAPOLB | |
| SCHEMBL4411156 | 0.77 | SMN1; SMN2 (0.42) | RAB9AHPGDL3MBTL1GAAPOLB | |
| SCHEMBL4357915 | 0.77 | KMT2A (0.40) | RAB9AHPGDL3MBTL1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385109-B1 | A group of esterases for the enantioselective production of fine and speciality chemicals | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2015-12-02 | — | — | EP | disclosed |
| EP-2377930-B1 | A group of esterases for the enantioselective production of fine and speciality chemicals | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-9193961-B2 | Polynucleotides encoding enantioselective carboxylesterases and methods of making same | B.R.A.I.N. AG (DE) | 2015-11-24 | — | — | US | disclosed |
| EP-2013337-B1 | A GROUP OF ESTERASES FOR THE ENANTIOSELECTIVE PRODUCTION OF FINE AND SPECIALITY CHEMICALS | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2013-03-27 | — | — | EP | disclosed |
| EP-2385109-A2 | A group of esterases for the enantioselective production of fine and speciality chemicals | B.R.A.I.N. Biotechnology Research And Information Network AG (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-2377930-A1 | A group of esterases for the enantioselective production of fine and speciality chemicals | B.R.A.I.N. Biotechnology Research And Information Network AG (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20090311745-A1 | GROUP OF ESTERASES FOR THE ENANTIOSELECTIVE PRODUCTION OF FINE AND SPECIALITY CHEMICALS | B.R.A.I.N AG (DE) | 2009-12-17 | — | — | US | disclosed |