Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482828 | 0.81 | RAB9A (0.43) | HPGDSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL2482835 | 0.81 | RAB9A (0.43) | HPGDSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL2482831 | 0.81 | RAB9A (0.43) | HPGDSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL8171703 | 0.80 | SLC6A3 (0.34) | HPGDSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL1811076 | 0.79 | — | — | |
| SCHEMBL17074314 | 0.76 | SLC6A3 (0.45) | HPGDSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL4411156 | 0.75 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL1581435 | 0.74 | SLC6A3 (0.38) | HPGDSMN1; SMN2ALDH1A1SLC6A3KMT2A | |
| SCHEMBL27901822 | 0.71 | ALDH1A1 (0.34) | HPGDSMN1; SMN2ALDH1A1L3MBTL1SLC6A3 | |
| SCHEMBL28583502 | 0.71 | EPHX1 (0.35) | SMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405860-B1 | OPHTHALMOLOGICAL COMPOSITION AND OPHTHALMOLOGICAL LENS | ZEISS CARL MEDITEC AG (DE) | 2013-09-25 | — | — | EP | disclosed |
| EP-2199834-B1 | Ophthalmological composition and ophthalmologic lens | ZEISS CARL MEDITEC AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2225293-B1 | COPOLYMER AND OPHTHALMOLOGICAL COMPOSITION | ZEISS CARL MEDITEC AG (DE) | 2012-02-08 | — | — | EP | disclosed |
| US-20110028667-A1 | Copolymer and Ophthalmological Composition | *ACRI.TEC GMBH (DE) | 2011-02-03 | — | — | US | disclosed |
| EP-2225293-A2 | COPOLYMER AND OPHTHALMOLOGICAL COMPOSITION | *Acri. Tec GmbH (DE) | 2010-09-08 | — | — | EP | disclosed |
| EP-2199834-A1 | Ophthalmological composition and ophthalmologic lens | *Acri. Tec GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009074520-A2 | COPOLYMER AND OPHTHALMOLOGICAL COMPOSITION | *ACRI.TEC GMBH (DE) | 2009-06-18 | — | — | WO | disclosed |