Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SELL | P14151 | 1/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | FABP2 | P12104 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822958 | 0.83 | MAPT (0.38) | KDM4EALDH1A1HSD17B10HPGDTTR | |
| SCHEMBL4556197 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDSELL | |
| SCHEMBL109811 | 0.83 | CLCN2 (0.49) | KDM4EALDH1A1HSD17B10HPGDTTR | |
| SCHEMBL18529852 | 0.82 | SELL (0.56) | KDM4EALDH1A1HSD17B10HPGDSELL | |
| SCHEMBL29814908 | 0.81 | CLCN2 (0.47) | KDM4EALDH1A1HSD17B10HPGDTTR | |
| SCHEMBL1834641 | 0.81 | CLCN2 (0.47) | KDM4EALDH1A1HSD17B10HPGDTTR | |
| SCHEMBL30083685 | 0.80 | ALDH1A1 (0.65) | KDM4EALDH1A1HSD17B10HPGDSELL | |
| SCHEMBL857301 | 0.80 | ALDH1A1 (0.65) | KDM4EALDH1A1HSD17B10HPGDSELL | |
| SCHEMBL29163182 | 0.80 | MAPK1 (0.53) | KDM4EALDH1A1HSD17B10HPGDTTR | |
| SCHEMBL9685948 | 0.79 | CLCN2 (0.46) | KDM4EALDH1A1HSD17B10HPGDTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376428-A2 | NEW INHIBITORS FOR TREATING DISEASES ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN | Universitätsklinikum Münster (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066909-A2 | NEW INHIBITORS FOR TREATING DISEASES ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN | Universitätsklinikum Münster (DE) | 2010-06-17 | — | — | WO | disclosed |
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |