Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22799778 | 0.86 | CYP3A4 (0.50) | CYP3A4L3MBTL1MAPTGAAALDH1A1 | |
| SCHEMBL7865177 | 0.85 | L3MBTL1 (0.54) | CYP3A4L3MBTL1AKR1C3CYP19A1MAPT | |
| SCHEMBL4622029 | 0.81 | L3MBTL1 (0.50) | CYP3A4L3MBTL1AKR1C3CYP19A1MAPT | |
| Benzophenone SCHEMBL11875971 | 0.80 | ALDH1A1 (0.56) | CYP3A4L3MBTL1MAPTGAAALDH1A1 | |
| SCHEMBL9358998 | 0.80 | L3MBTL1 (0.52) | CYP3A4L3MBTL1AKR1C3CYP19A1MAPT | |
| SCHEMBL943893 | 0.79 | AKR1C3 (0.50) | L3MBTL1AKR1C3CYP19A1MAPTGAA | |
| SCHEMBL170063 | 0.79 | AKR1C3 (0.50) | L3MBTL1AKR1C3CYP19A1MAPTGAA | |
| SCHEMBL30560007 | 0.79 | AKR1C3 (0.50) | L3MBTL1AKR1C3CYP19A1MAPTGAA | |
| SCHEMBL22799781 | 0.79 | ALDH1A1 (0.51) | CYP3A4GAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL22799660 | 0.79 | CYP3A4 (0.46) | CYP3A4L3MBTL1MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | JANSSEN BIOPHARMA INC (US) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002409-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | ACE, PNP, FEN1 | CYP3A4 88/4885L3MBTL1 2124/4885AKR1C3 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.