Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | LIG1 | P18858 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622029 | 0.91 | L3MBTL1 (0.50) | L3MBTL1AKR1C3GAAMAPTCYP19A1 | |
| SCHEMBL9358998 | 0.90 | L3MBTL1 (0.52) | L3MBTL1AKR1C3GAAMAPTCYP19A1 | |
| SCHEMBL4729690 | 0.89 | L3MBTL1 (0.51) | L3MBTL1AKR1C3GAAMAPTCYP19A1 | |
| SCHEMBL24834273 | 0.85 | CYP3A4 (0.46) | L3MBTL1AKR1C3GAAMAPTCYP19A1 | |
| SCHEMBL1558507 | 0.85 | L3MBTL1 (0.51) | L3MBTL1AKR1C3GAAMAPTCYP19A1 | |
| SCHEMBL27482417 | 0.84 | PTPRC (0.54) | L3MBTL1AKR1C3GAAMAPTALDH1A1 | |
| SCHEMBL11036287 | 0.84 | AKR1C3 (0.61) | L3MBTL1AKR1C3GAAMAPTCYP19A1 | |
| SCHEMBL6666740 | 0.82 | L3MBTL1 (0.49) | L3MBTL1AKR1C3GAAMAPTCYP19A1 | |
| SCHEMBL23453516 | 0.82 | TP53 (0.59) | GAAMAPTALDH1A1CYP2C9KMT2A | |
| SCHEMBL28423359 | 0.82 | AKR1C3 (0.59) | L3MBTL1AKR1C3GAAMAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284910-B1 | FARNESYL TRANSFERASE INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2001-09-04 | — | — | US | disclosed |
| EP-1069916-A2 | LATENT REACTIVE BLOOD COMPATIBLE AGENTS | SurModics, Inc. (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-0585436-B1 | IMMOBILIZATION OF CHEMICAL SPECIES IN CROSSLINKED MATRICES | SURMODICS INC (US) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999047176-A2 | LATENT REACTIVE BLOOD COMPATIBLE AGENTS | SURMODICS, INC. (US) | 1999-09-23 | — | — | WO | disclosed |
| US-5563056-A | FORMING A MATRIX HAVING FIRST CHEMICAL SPECIES COVALENTLY IMMOBILIZED AND INCLUDES FREE MOLECULES OF SECOND CHEMICAL SPECIES, GRADUALLY RELEASING THE SECOND SPECIES MOLECULE FROM MATRIX | BSI CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0585436-A4 | — | — | 1994-03-30 | — | — | EP | disclosed |
| EP-0585436-A1 | IMMOBILIZATION OF CHEMICAL SPECIES IN CROSSLINKED MATRICES | BIO-METRIC SYSTEMS, INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1993016176-A1 | IMMOBILIZATION OF CHEMICAL SPECIES IN CROSSLINKED MATRICES | BIO-METRIC SYSTEMS, INC. (US) | 1993-08-19 | — | — | WO | disclosed |