Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.59 |
| ▸ | LMNA | P02545 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.59 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.56 |
| ▸ | TP53 | P04637 | 6/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.54 |
| ▸ | KLK1 | P06870 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 9/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15987441 | 0.82 | RAB9A (0.66) | RAB9ALMNAMAPTKDM4EKLF5 | |
| SCHEMBL4114205 | 0.75 | RAB9A (0.81) | RAB9ALMNAMAPTKDM4EKLF5 | |
| SCHEMBL266418 | 0.72 | RAB9A (0.54) | RAB9ALMNAMAPTKDM4EKLF5 | |
| SCHEMBL24834926 | 0.72 | TSHR (0.41) | RAB9ALMNAMAPTKDM4ENPC1 | |
| SCHEMBL17456958 | 0.69 | SMN1; SMN2 (1.00) | RAB9ALMNAMAPTKDM4EKLF5 | |
| SCHEMBL20741111 | 0.69 | SMN1; SMN2 (0.61) | RAB9ALMNAMAPTKDM4EKLF5 | |
| SCHEMBL10916089 | 0.67 | NPC1 (0.49) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL4494042 | 0.67 | PDK1 (0.43) | LMNAKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL13936174 | 0.67 | PDK1 (0.43) | LMNAKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2023366 | 0.66 | SMN1; SMN2 (0.72) | LMNAMAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274251-A1 | POLYCYCLIC COMPOUND FOR INHIBITING RNA HELICASE DHX33, AND APPLICATION OF COMPOUND | 深圳开悦生命科技有限公司 | 2023-01-05 | — | — | WO | disclosed |