Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | KLK1 | P06870 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24834367 | 0.72 | RAB9A (0.59) | TSHRLMNASMN1; SMN2TDP1MAPT | |
| SCHEMBL19048267 | 0.68 | NOTUM (0.46) | TSHRGAALMNASMN1; SMN2TDP1 | |
| SCHEMBL13947267 | 0.66 | CA12 (0.33) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL16005033 | 0.64 | CA12 (0.40) | KMT2A | |
| SCHEMBL828580 | 0.62 | EGFR (0.41) | TSHRTDP1MAPTALDH1A1HSD17B10 | |
| SCHEMBL14886580 | 0.61 | NOTUM (0.47) | TSHRLMNASMN1; SMN2NOTUMMAPT | |
| SCHEMBL6350428 | 0.61 | CYP2C9 (0.41) | MEN1KMT2ANPSR1 | |
| SCHEMBL15568745 | 0.61 | KMT2A (0.34) | GAALMNAMAPTMEN1KMT2A | |
| SCHEMBL1407974 | 0.60 | TP53 (0.34) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL15567724 | 0.60 | GPR35 (0.39) | GAASMN1; SMN2TDP1NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274251-A1 | POLYCYCLIC COMPOUND FOR INHIBITING RNA HELICASE DHX33, AND APPLICATION OF COMPOUND | 深圳开悦生命科技有限公司 | 2023-01-05 | — | — | WO | disclosed |