Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24834599 | 0.94 | NLRP3 (0.42) | NLRP3SMN1; SMN2TSHRHTTGAA | |
| SCHEMBL24834600 | 0.87 | TSHR (0.36) | NLRP3SMN1; SMN2TSHRHTTGAA | |
| SCHEMBL24834529 | 0.87 | NLRP3 (0.52) | NLRP3SMN1; SMN2TSHRHTTGAA | |
| SCHEMBL24834575 | 0.85 | NLRP3 (0.51) | NLRP3TSHRKMT2ATP53HPGD | |
| SCHEMBL29348126 | 0.82 | NLRP3 (0.44) | NLRP3SMN1; SMN2TSHRHTTMAPT | |
| SCHEMBL24834877 | 0.81 | NLRP3 (0.53) | NLRP3P2RX3 | |
| SCHEMBL24834598 | 0.81 | P2RX3 (0.38) | NLRP3SMN1; SMN2TSHRHTTGAA | |
| SCHEMBL24834573 | 0.79 | NLRP3 (0.52) | NLRP3KMT2AAKR1B1 | |
| SCHEMBL29348128 | 0.79 | NLRP3 (0.46) | NLRP3SMN1; SMN2TSHRHTTGAA | |
| SCHEMBL29348127 | 0.79 | NLRP3 (0.46) | NLRP3SMN1; SMN2TSHRHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023275230-A1 | 5-OXO-PYRIDO[2,3-D]PYRIDAZIN-6(5H)-YL ACETAMIDES | JANSSEN PHARMACEUTICA NV (BE) | 2023-01-05 | — | — | WO | disclosed |