Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 17/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24834880 | 0.99 | PLAT (0.36) | PLATPDE10APROKR1 | |
| SCHEMBL29785416 | 0.99 | PLAT (0.36) | PLATPDE10APROKR1 | |
| SCHEMBL24834841 | 0.93 | PLAT (0.35) | PLAT | |
| SCHEMBL29785449 | 0.90 | PLAT (0.34) | PLATPDE10APROKR1 | |
| SCHEMBL29785492 | 0.90 | PLAT (0.36) | PLATPDE10APROKR1 | |
| SCHEMBL24834859 | 0.90 | PLAT (0.36) | PLATPDE10APROKR1 | |
| SCHEMBL24834809 | 0.90 | PLAT (0.34) | PLATPDE10APROKR1 | |
| SCHEMBL29785521 | 0.89 | PLAT (0.35) | PLATPDE10APROKR1 | |
| SCHEMBL23415043 | 0.89 | PLAT (0.35) | PLATPDE10APROKR1 | |
| SCHEMBL23415597 | 0.89 | ALDH1A1 (0.33) | PLATPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002396-A1 | THERAPEUTIC COMPOUNDS | GENENTECH, INC. (US) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002396-A1 | THERAPEUTIC COMPOUNDS | YAP1, YES1, TEAD2 | PLAT 3745/4885PDE10A 2899/4885PROKR1 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.