Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23207892 | 0.82 | NR1H4 (0.51) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL25628053 | 0.81 | LOXL2 (0.49) | MAPTCYP4A11LOXL2CYP3A4CYP2C9 | |
| SCHEMBL12326116 | 0.80 | CA1 (0.53) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL29244668 | 0.80 | CA1 (0.53) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL27358541 | 0.80 | CA1 (0.53) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL24862002 | 0.80 | ACACB (0.52) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL28351919 | 0.79 | MEN1 (0.49) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL21147155 | 0.79 | CA1 (0.52) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL1791209 | 0.79 | L3MBTL1 (0.52) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL16684851 | 0.79 | L3MBTL1 (0.52) | MAPTCA1CA2TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |