Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673788 | 0.83 | TSHR (0.44) | TSHRCYP3A4VCAM1CASP6TDP1 | |
| SCHEMBL7734099 | 0.83 | VCAM1 (0.44) | TSHRCYP3A4VCAM1TDP1MAPK1 | |
| SCHEMBL7153973 | 0.82 | GPR35 (0.58) | TSHRCYP3A4VCAM1TDP1MAPK1 | |
| SCHEMBL697848 | 0.82 | ALDH1A1 (0.58) | VCAM1CASP6TDP1ATMALDH1A1 | |
| SCHEMBL5163347 | 0.82 | TSHR (0.56) | TSHRCYP3A4VCAM1TDP1MAPK1 | |
| SCHEMBL7151564 | 0.82 | MAPK1 (0.58) | TSHRCYP3A4VCAM1MAPK1GPR35 | |
| SCHEMBL10348032 | 0.82 | TSHR (0.60) | TSHRCYP3A4VCAM1TDP1MAPK1 | |
| SCHEMBL698857 | 0.82 | VCAM1 (0.71) | TSHRVCAM1TDP1MAPK1MAPT | |
| SCHEMBL29217568 | 0.82 | TDP1 (0.60) | TSHRCYP3A4VCAM1TDP1MAPK1 | |
| SCHEMBL27799226 | 0.82 | MAPT (0.60) | TSHRCYP3A4VCAM1TDP1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035614-C | Benzylidene derivatives | SHIONOGI & CO (JP) | 1997-08-13 | — | — | CN | claimed |
| EP-0595546-B1 | Benzylidene derivatives | SHIONOGI & CO (JP) | 1996-03-20 | — | — | EP | claimed |
| US-5418230-A | Antiinflammatory | SHIONOGI & CO., LTD. (JP) | 1995-05-23 | — | — | US | claimed |
| US-4472386-A | 5-Fluoro-(β-uridine or 2'-deoxy-β-uridine) derivatives, a process for producing the same and a carcinostatic agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | claimed |
| CN-110577489-B | Synthetic method of narcotic analgesic | 宜昌人福药业有限责任公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-112079823-B | Near-infrared frequency up-conversion fluorescence molecular probe, preparation method and application | 中国药科大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-112079823-A | Near-infrared frequency up-conversion fluorescence molecular probe, preparation method and application | 中国药科大学 | 2020-12-15 | — | — | CN | disclosed |
| CN-110577489-A | Synthetic method of narcotic analgesic | 宜昌人福药业有限责任公司 | 2019-12-17 | — | — | CN | disclosed |
| US-9045520-B2 | Synthesis of purine nucleosides | GILEAD PHARMASSET LLC (US) | 2015-06-02 | — | — | US | disclosed |
| CN-104557472-A | Adamantane derivative, preparation method and application in epoxy resin | UNIV BEIJING CHEMICAL | 2015-04-29 | — | — | CN | disclosed |
| US-8716263-B2 | Synthesis of purine nucleosides | GILEAD PHARMASSET LLC (US) | 2014-05-06 | — | — | US | disclosed |
| EP-2671888-A1 | 3',5'-cyclic nucleoside phosphate analogues | Gilead Pharmasset LLC (US) | 2013-12-11 | — | — | EP | disclosed |
| US-6114566-A | 4-cyano-3-hydroxybutanoyl hydrazines, derivatives and process for the preparation thereof | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2000-09-05 | — | — | US | disclosed |
| EP-1026162-A1 | ANTIRHEUMATIC | SHIONOGI & CO., LTD. (JP) | 2000-08-09 | — | — | EP | disclosed |
| CN-1035614-C | Benzylidene derivatives | SHIONOGI & CO (JP) | 1997-08-13 | — | — | CN | disclosed |
| EP-0595546-B1 | Benzylidene derivatives | SHIONOGI & CO (JP) | 1996-03-20 | — | — | EP | disclosed |
| CN-1092414-A | Benzylidene derivatives | SHIONOGI & CO (JP) | 1994-09-21 | — | — | CN | disclosed |
| EP-0595546-A1 | Benzylidene derivatives | SHIONOGI & CO., LTD. (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-4472386-A | 5-Fluoro-(β-uridine or 2'-deoxy-β-uridine) derivatives, a process for producing the same and a carcinostatic agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0092830-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |