Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414286 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL414603 | 0.74 | BCHE (0.39) | — | |
| SCHEMBL2513835 | 0.74 | NLRP3 (0.40) | — | |
| SCHEMBL413583 | 0.71 | NPC1 (0.50) | — | |
| SCHEMBL415868 | 0.71 | NPC1 (0.50) | MEN1KMT2A | |
| SCHEMBL418476 | 0.70 | ALDH1A1 (0.34) | KMT2A | |
| SCHEMBL415495 | 0.69 | NPC1 (0.45) | MEN1KMT2A | |
| SCHEMBL414437 | 0.69 | TDP1 (0.45) | MEN1KMT2A | |
| SCHEMBL413418 | 0.67 | ACHE (0.52) | MEN1KMT2A | |
| SCHEMBL412451 | 0.67 | ACHE (0.54) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | disclosed |