Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117527 | 0.84 | ACHE (0.59) | ACHEERN1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL5359171 | 0.80 | RAB9A (0.33) | ALDH1A1SMN1; SMN2LMNATUBB1CYP3A4 | |
| SCHEMBL17864550 | 0.77 | ACHE (0.52) | ACHEERN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8056786 | 0.77 | ACHE (0.52) | ACHEERN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14430069 | 0.74 | ERN1 (0.53) | ACHEERN1ALDH1A1LMNANFE2L2 | |
| SCHEMBL11962257 | 0.72 | ACHE (0.52) | ACHEERN1ALDH1A1TUBB1TUBB4A | |
| SCHEMBL20226996 | 0.71 | ACHE (0.45) | ACHEERN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19504310 | 0.71 | ACHE (0.45) | ACHEERN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30994812 | 0.69 | ACHE (0.43) | ACHEERN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17027285 | 0.69 | ACHE (0.43) | ACHEERN1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278438-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD (US) | 2023-01-05 | — | — | WO | disclosed |