SCHEMBL2484068

SCHEMBL2484068

O=C(OC(Cc1ccccc1)(c1ccccc1)c1ccccc1)OC(Cc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP2C9 P11712 1/20 0.48
HIF1A Q16665 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
RECQL P46063 2/20 0.41
CYP3A4 P08684 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
KIF11 P52732 1/20 0.41
KCNH2 Q12809 2/20 0.40
OPRM1 P35372 2/20 0.40
OPRD1 P41143 2/20 0.40
MRGPRX2 Q96LB1 1/20 0.40
CHRM3 P20309 1/20 0.40
HRH2 P25021 1/20 0.40
HTR2A P28223 1/20 0.40
ADRA1A P35348 1/20 0.40
OPRK1 P41145 1/20 0.40
FDPS P14324 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21142143 0.90 KIF11 (0.45) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL5846769 0.89 CYP2C19 (0.48) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL12478787 0.85 CYP2C19 (0.46) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL9728260 0.85 HIF1A (0.47) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL9189250 0.85 ALDH1A1 (0.47) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2
Phosphine SCHEMBL6248436 0.84 ALDH1A1 (0.46) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL6932097 0.81 CYP1A2 (0.42) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL1535931 0.81 ALDH1A1 (0.43) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2
Hydrochloric Acid SCHEMBL3839265 0.81 MAPK1 (0.49) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2
Hydrochloric Acid SCHEMBL1249577 0.81 CYP1A2 (0.42) CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1323846-B1 Process for preparing metal coatings from liquid solutions utilizing cold plasma AMT HOLDINGS INC (US) 2011-10-19 EP disclosed
US-20070184208-A1 PROCESS FOR PREPARING METAL COATINGS FROM LIQUID SOLUTIONS UTILIZING COLD PLASMA AMT HOLDINGS, INC. 2007-08-09 US disclosed