Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728260 | 0.81 | HIF1A (0.47) | CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL2484068 | 0.81 | CYP1A2 (0.48) | CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL5846769 | 0.81 | CYP2C19 (0.48) | CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL9189250 | 0.78 | ALDH1A1 (0.47) | CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL12478787 | 0.78 | CYP2C19 (0.46) | CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL1535931 | 0.77 | ALDH1A1 (0.43) | CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| Phosphine SCHEMBL6248436 | 0.77 | ALDH1A1 (0.46) | CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL27379939 | 0.75 | KMT2A (0.39) | CYP1A2CYP2C19HIF1AKIF11ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3839265 | 0.74 | MAPK1 (0.49) | CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| Phosphine SCHEMBL8857165 | 0.74 | CYP1A2 (0.42) | CYP1A2CYP2C19CYP2C9HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645548-B1 | METHODS FOR PREPARING BILE ACIDS | MEDYTOX INC (KR) | 2023-11-29 | — | — | EP | disclosed |
| US-20220009957-A1 | Methods for Preparing Bile Acids | MEDYTOX INC. (KR) | 2022-01-13 | — | — | US | disclosed |
| US-11161872-B2 | Methods for preparing bile acids | MEDYTOX INC. (KR) | 2021-11-02 | — | — | US | disclosed |
| US-20200369712-A1 | METHODS FOR PREPARING BILE ACIDS | WUXI APPTEC (SHANGHAI) CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| EP-3645548-A1 | METHODS FOR PREPARING BILE ACIDS | Medytox Inc. (KR) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019024920-A1 | METHODS FOR PREPARING BILE ACIDS | MEDYTOX INC. (KR) | 2019-02-07 | — | — | WO | disclosed |
| EP-1363869-B1 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | WEYLCHEM LAMOTTE (FR) | 2015-04-08 | — | — | EP | disclosed |
| EP-1363869-A2 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | Clariant (France) S.A. (FR) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002067847-A2 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | CLARIANT (FRANCE) (FR) | 2002-09-06 | — | — | WO | disclosed |
| EP-0665224-A1 | PYRIMIDINE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-4021479-A | ANTIPHLOGISTICS AND ANTIPROLIFERATIVES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009957-A1 | Methods for Preparing Bile Acids | DHCR7, CYP46A1, CYP27A1 | CYP1A2 100/4885CYP2C19 115/4885CYP2C9 78/4885 |
| US-20200369712-A1 | METHODS FOR PREPARING BILE ACIDS | DHCR7, CYP46A1, CYP27A1 | CYP1A2 100/4885CYP2C19 115/4885CYP2C9 78/4885 |
| US-11161872-B2 | Methods for preparing bile acids | DHCR7, CYP46A1, CYP27A1 | CYP1A2 100/4885CYP2C19 115/4885CYP2C9 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.