SCHEMBL2484069

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756171	0.90	HTT (0.46)	HTTALDH1A1LMNAHPGDTP53
	SCHEMBL756172	0.90	HTT (0.46)	HTTALDH1A1LMNAHPGDTP53
	SCHEMBL16921570	0.86	LMNA (0.44)	HTTALDH1A1LMNATP53KMT2A
	SCHEMBL16925397	0.85	ALDH1A1 (0.42)	HTTALDH1A1LMNAHPGDKMT2A
	SCHEMBL755066	0.84	HTT (0.39)	HTTALDH1A1LMNAKMT2AGAA
	SCHEMBL755067	0.84	HTT (0.39)	HTTALDH1A1LMNAKMT2AGAA
	SCHEMBL2490056	0.84	ALDH1A1 (0.39)	HTTALDH1A1LMNAHPGDTP53
	SCHEMBL2487742	0.83	HDAC1 (0.40)	HTTALDH1A1LMNAKMT2AGAA
	SCHEMBL2514379	0.82	HTT (0.41)	HTTALDH1A1KMT2AMAPTRAB9A
	SCHEMBL2486904	0.81	HTT (0.39)	HTTALDH1A1LMNATP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.