Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GOT1 | P17174 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477411 | 0.84 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CADRA1APRKCZ | |
| SCHEMBL8352436 | 0.76 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1APRKCZ | |
| SCHEMBL30743841 | 0.76 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1APRKCZ | |
| SCHEMBL27844122 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL27034898 | 0.74 | KDM4E (0.62) | ADRA2AADRA2BADRA2CADRA1APRKCZ | |
| SCHEMBL2791578 | 0.73 | ADRA2A (0.80) | ADRA2AADRA2BADRA2CADRA1APRKCZ | |
| SCHEMBL28594117 | 0.73 | ALDH1A1 (0.56) | ADRA2AADRA2BADRA2CADRA1AKDM4E | |
| SCHEMBL1996604 | 0.72 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CADRA1APRKCZ | |
| SCHEMBL1996607 | 0.72 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CADRA1APRKCZ | |
| SCHEMBL13993988 | 0.72 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CADRA1APRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002378-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | STORM THERAPEUTICS LIMITED (GB) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002378-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | METTL3, DIMT1, TPMT | ADRA2A 4389/4885ADRA2B 4446/4885ADRA2C 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.