Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15859356 | 0.81 | CA2 (0.49) | MAP4K4ALDH1A1CYP1A2ADRB2BCHE | |
| SCHEMBL29778343 | 0.81 | CHRM2 (0.49) | MAP4K4HTR1APRMT6CYP1A2CYP2C19 | |
| SCHEMBL16264585 | 0.81 | CHRM2 (0.45) | MAP4K4HTR1APRMT6CYP1A2CYP2C19 | |
| SCHEMBL16264621 | 0.81 | CHRM2 (0.49) | MAP4K4HTR1APRMT6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL29778279 | 0.80 | CHRM2 (0.44) | MAP4K4HTR1APRMT6CYP1A2CYP2C19 | |
| SCHEMBL1566434 | 0.78 | TAAR1 (0.62) | ALDH1A1CYP1A2CYP2C19SLC2A1HDAC1 | |
| SCHEMBL552305 | 0.78 | TAAR1 (0.62) | ALDH1A1CYP1A2CYP2C19KDM4ECYP2D6 | |
| SCHEMBL21648402 | 0.77 | SCN8A (0.49) | MAP4K4HTR1ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL13416723 | 0.76 | ALDH1A1 (0.56) | ALDH1A1CYP1A2ADRB2CYP2C19GAA | |
| Hydrochloric Acid SCHEMBL29885630 | 0.76 | SCN8A (0.48) | MAP4K4HTR1ACYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725010-B2 | Polyheterocyclic compounds as METTL3 inhibitors | STORM THERAPEUTICS LIMITED (GB) | 2023-08-15 | — | — | US | disclosed |
| US-20230002378-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | STORM THERAPEUTICS LIMITED (GB) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002378-A1 | POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS | METTL3, DIMT1, TPMT | MAP4K4 3645/4885HTR1A 2943/4885PRMT6 69/4885 |
| US-11725010-B2 | Polyheterocyclic compounds as METTL3 inhibitors | METTL3, DIMT1, TPMT | MAP4K4 3645/4885HTR1A 2943/4885PRMT6 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.