Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16119729 | 0.78 | CTSS (0.47) | EPHX1ACHECTSSCTSLCTSK | |
| SCHEMBL17888970 | 0.77 | CTSS (0.46) | EPHX1ACHECTSSCTSLSMN1; SMN2 | |
| SCHEMBL10772419 | 0.75 | EPHX1 (0.43) | EPHX1ACHEALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL19105332 | 0.74 | TSHR (0.45) | EPHX1TSHRALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL26293402 | 0.74 | EPHX1 (0.47) | EPHX1ACHE | |
| SCHEMBL8326965 | 0.74 | CTSC (0.56) | CTSSCTSLCTSK | |
| SCHEMBL17449776 | 0.74 | CTSK (0.55) | CTSSCTSLCTSK | |
| SCHEMBL21359118 | 0.74 | HRH3 (0.42) | EPHX1ACHESMN1; SMN2NPC1HPGD | |
| SCHEMBL3238391 | 0.74 | CTSS (0.50) | CTSSCTSLCTSK | |
| SCHEMBL3238402 | 0.74 | CTSS (0.50) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376477-A2 | STEREOSELECTIVE SYNTHESIS OF PIPERIDINE DERIVATIVES | Taigen Biotechnology Co., Ltd. (TW) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010077798-A2 | STEREOSELECTIVE SYNTHESIS OF PIPERIDINE DERIVATIVES | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2010-07-08 | — | — | WO | disclosed |