Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 6/20 | 0.56 |
| ▸ | CTSK | P43235 | 10/20 | 0.54 |
| ▸ | CTSL | P07711 | 9/20 | 0.54 |
| ▸ | CTSS | P25774 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CTSH | P09668 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407256 | 0.88 | CTSK (0.52) | CTSKCTSLCTSSCYP1A2CYP3A4 | |
| SCHEMBL6318841 | 0.82 | CTSL (0.65) | CTSCCTSKCTSLCTSSCTSB | |
| SCHEMBL392814 | 0.82 | CTSL (0.65) | CTSCCTSKCTSLCTSSCTSB | |
| SCHEMBL6312394 | 0.82 | CTSL (0.65) | CTSCCTSKCTSLCTSSCTSB | |
| SCHEMBL6021250 | 0.81 | CTSL (0.56) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6021245 | 0.81 | CTSL (0.57) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6021077 | 0.81 | CTSS (0.74) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5564837 | 0.80 | CTSC (0.66) | CTSCCTSKCTSLCTSSCYP1A2 | |
| SCHEMBL5564840 | 0.80 | CTSC (0.66) | CTSCCTSKCTSLCTSSCYP1A2 | |
| SCHEMBL844471 | 0.80 | ITGB3 (0.58) | CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948496-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDONE COMPOUNDS AND METHODS OF USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998024780-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDINONE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |