Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 14/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769869 | 0.85 | EPHX1 (0.47) | EPHX1RAB9ANPC1SMN1; SMN2ACHE | |
| SCHEMBL6576436 | 0.84 | EPHX1 (0.53) | EPHX1RAB9ANPC1SMN1; SMN2ACHE | |
| SCHEMBL2484624 | 0.84 | EPHX1 (0.46) | EPHX1RAB9ANPC1SMN1; SMN2ACHE | |
| SCHEMBL28481312 | 0.82 | EPHX1 (0.52) | EPHX1RAB9ANPC1SMN1; SMN2ACHE | |
| SCHEMBL4957666 | 0.76 | EPHX1 (0.50) | EPHX1RAB9ANPC1SMN1; SMN2ACHE | |
| SCHEMBL2650736 | 0.76 | ACHE (0.56) | EPHX1RAB9ANPC1SMN1; SMN2ACHE | |
| SCHEMBL1136659 | 0.75 | SMN1; SMN2 (0.45) | EPHX1RAB9ANPC1SMN1; SMN2ACHE | |
| SCHEMBL4451188 | 0.75 | RAB9A (0.61) | EPHX1RAB9ANPC1SMN1; SMN2ACHE | |
| SCHEMBL283132 | 0.74 | — | — | |
| SCHEMBL9565516 | 0.74 | RAB9A (0.43) | EPHX1RAB9ANPC1SMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376123-A2 | OLIGOSACCHARIDE-PROTEIN CONJUGATES | Genzyme Corporation (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010075010-A2 | OLIGOSACCHARIDE-PROTEIN CONJUGATES | GENZYME CORPORATION (US) | 2010-07-01 | — | — | WO | disclosed |
| EP-1115740-A1 | SYNTHETIC PEPTIDES, CONJUGATION REAGENTS AND METHODS | The Regents of the University of California (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017226-A1 | SYNTHETIC PEPTIDES, CONJUGATION REAGENTS AND METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-03-30 | — | — | WO | disclosed |