Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 5/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | NUDT1 | P36639 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TOP2A | P11388 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CDK1 | P06493 | 3/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24846509 | 0.94 | CYP1A2 (0.88) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL2115657 | 0.88 | PIN1 (1.00) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL9872864 | 0.80 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL27485471 | 0.79 | CDK2 (0.65) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL13742763 | 0.78 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL24846960 | 0.78 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL24846493 | 0.78 | ENPP1 (0.73) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL24846433 | 0.77 | CYP1A2 (0.79) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL24846524 | 0.77 | PIN1 (0.75) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL16758710 | 0.77 | MAP3K5 (0.69) | CYP1A2CYP3A4CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ATEN PORUS LIFESCIENCES PVT. LTD. (IN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002387-A1 | 2-AMINO-S6-SUBSTITUTED THIOPURINE COMPOUNDS AS INHIBITORS OF THE ENPP1 PROTEIN | ENPP1, ENPP3, PNP | CYP1A2 3194/4885CYP3A4 3336/4885CYP2C19 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.