Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482383 | 0.81 | KDM1A (0.39) | KDM1AALDH1A1ABCB1KDM4EUBE2M | |
| SCHEMBL12332655 | 0.79 | KDM1A (0.36) | KDM1ANPSR1POLBMAPTRECQL | |
| SCHEMBL14752771 | 0.77 | KDM4E (0.43) | KDM1ANPSR1POLBMAPTRECQL | |
| SCHEMBL2451498 | 0.73 | HPGD (0.54) | KDM1ANPSR1MAPTALDH1A1LMNA | |
| SCHEMBL14752773 | 0.73 | HPGD (0.46) | KDM1ANPSR1MAPTALDH1A1LMNA | |
| SCHEMBL2489442 | 0.72 | ALDH1A1 (0.44) | KDM1ANPSR1POLBMAPTALDH1A1 | |
| SCHEMBL14755170 | 0.71 | KDM1A (0.34) | KDM1ANPSR1POLBMAPTRECQL | |
| SCHEMBL12332804 | 0.71 | KDM4E (0.31) | NPSR1KDM4ERAB9A | |
| SCHEMBL13085024 | 0.68 | NPSR1 (0.46) | NPSR1POLBMAPTRECQLALDH1A1 | |
| SCHEMBL14752786 | 0.66 | ALDH1A1 (0.37) | NPSR1POLBMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376402-B2 | 1, 2, 4-triazole derivatives and their anti-microbial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-28 | — | — | US | disclosed |
| US-9376402-B2 | 1, 2, 4-triazole derivatives and their anti-microbial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-28 | — | — | US | disclosed |
| US-9376402-B2 | 1, 2, 4-triazole derivatives and their anti-microbial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-28 | — | — | US | disclosed |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | COUNCIL SCIENT IND RES (IN) | 2015-03-12 | — | — | US | disclosed |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | COUNCIL SCIENT IND RES (IN) | 2015-03-12 | — | — | US | disclosed |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | COUNCIL SCIENT IND RES (IN) | 2015-03-12 | — | — | US | disclosed |
| US-8865910-B2 | 1, 2, 4-triazole derivatives and their anti mycobacterial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-21 | — | — | US | disclosed |
| US-8865910-B2 | 1, 2, 4-triazole derivatives and their anti mycobacterial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-21 | — | — | US | disclosed |
| US-8865910-B2 | 1, 2, 4-triazole derivatives and their anti mycobacterial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-21 | — | — | US | disclosed |
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-07 | — | — | US | disclosed |
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-07 | — | — | US | disclosed |
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-07 | — | — | US | disclosed |
| WO-2011111077-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-09-15 | — | — | WO | disclosed |
| WO-2011111077-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | NAT1, CBR3, NOX3 | KDM1A 3272/4885NPSR1 2605/4885POLB 415/4885 |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | CYP51A1, TALDO1, IL33 | KDM1A 2975/4885NPSR1 3899/4885POLB 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.