Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18634102 | 0.76 | NOS2 (0.35) | NOS2CCR1CCR5CCR8NOS3 | |
| SCHEMBL21711156 | 0.71 | NOS3 (0.48) | SMN1; SMN2NOS2CCR1CCR5CCR8 | |
| SCHEMBL23732288 | 0.70 | NOS2 (0.34) | NOS2CCR1CCR5CCR8NOS3 | |
| SCHEMBL26382871 | 0.69 | NOS2 (0.34) | NOS2CCR1CCR5CCR8NOS3 | |
| SCHEMBL20320657 | 0.69 | NOS2 (0.31) | NOS2CCR1CCR5CCR8NOS3 | |
| SCHEMBL21392754 | 0.68 | CCR1 (0.35) | SMN1; SMN2NOS2CCR1CCR5CCR8 | |
| SCHEMBL14421997 | 0.67 | NOS2 (0.31) | NOS2CCR1CCR5CCR8NOS3 | |
| SCHEMBL13771122 | 0.67 | NOS2 (0.31) | NOS2CCR1CCR5CCR8NOS3 | |
| SCHEMBL7235627 | 0.64 | NOS2 (0.45) | NOS2CCR1CCR5CCR8NOS3 | |
| SCHEMBL7235622 | 0.64 | NOS2 (0.45) | NOS2CCR1CCR5CCR8NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022246459-A9 | COMBINATION THERAPY | GENENTECH, INC. (US) | 2023-01-05 | — | — | WO | disclosed |