SCHEMBL24848725

SCHEMBL24848725

Cc1ccccc1-n1c2ccccc2c2cccc(-c3ccccc3)c21

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.47
FTO Q9C0B1 1/20 0.47
TSHR P16473 2/20 0.44
ALDH1A1 P00352 5/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 1/20 0.43
DUSP3 P51452 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
RAB9A P51151 1/20 0.40
HTR7 P34969 1/20 0.40
KDM4E B2RXH2 2/20 0.39
ATM Q13315 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
HTT P42858 1/20 0.39
MAPK14 Q16539 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24848726 0.88 PDCD1 (0.44) ALKBH5FTOALDH1A1L3MBTL1DUSP3
SCHEMBL17902070 0.87 KDM4E (0.48) ALKBH5FTOALDH1A1L3MBTL1LMNA
SCHEMBL20988508 0.85 ALKBH5 (0.43) ALKBH5FTOALDH1A1L3MBTL1DUSP3
SCHEMBL17995394 0.83 ALKBH5 (0.61) ALKBH5FTOTSHRALDH1A1L3MBTL1
SCHEMBL18020159 0.83 ALDH1A1 (0.40) ALKBH5FTOTSHRALDH1A1L3MBTL1
SCHEMBL12447618 0.83 POLB (0.44) TSHRALDH1A1L3MBTL1DUSP3SMN1; SMN2
SCHEMBL24311511 0.82 ALKBH5 (0.40) ALKBH5FTOTSHRALDH1A1L3MBTL1
SCHEMBL25028761 0.82 DUSP3 (0.43) ALDH1A1L3MBTL1LMNADUSP3KDM4E
SCHEMBL21742665 0.82 KDM4E (0.49) ALKBH5FTOL3MBTL1DUSP3RAB9A
SCHEMBL26570042 0.82 ALKBH5 (0.45) ALKBH5FTOTSHRALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230049161-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-16 US disclosed
US-20230041530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-09 US disclosed
US-20230002417-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 ALKBH5 2293/4885FTO 435/4885TSHR 398/4885
US-20230002417-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 ALKBH5 929/4885FTO 53/4885TSHR 4211/4885
US-20230049161-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, AOC2, OCIAD1 ALKBH5 1306/4885FTO 534/4885TSHR 2656/4885
US-20230041530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CHRM1 ALKBH5 4434/4885FTO 1697/4885TSHR 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.