Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | BCL3 | P20749 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413567 | 0.80 | PKM (0.49) | PKMLMNAALDH1A1MEN1HTT | |
| SCHEMBL417767 | 0.75 | ACHE (0.47) | LMNAALDH1A1MEN1KMT2AACHE | |
| SCHEMBL2485314 | 0.74 | — | — | |
| SCHEMBL417604 | 0.73 | TDP1 (0.38) | LMNAALDH1A1MEN1KMT2AACHE | |
| SCHEMBL415376 | 0.71 | ACHE (0.51) | MAPK1LMNAMEN1KMT2AACHE | |
| SCHEMBL413455 | 0.70 | ACHE (0.54) | LMNAMEN1KMT2AACHE | |
| SCHEMBL415861 | 0.69 | KDM4E (0.41) | MAPK1LMNAHTTKMT2AKDM4E | |
| SCHEMBL414439 | 0.69 | KMT2A (0.49) | ALDH1A1MEN1KMT2AACHE | |
| SCHEMBL414368 | 0.69 | ALDH1A1 (0.40) | LMNAALDH1A1MEN1KMT2AACHE | |
| SCHEMBL412453 | 0.68 | KDM4E (0.42) | ALDH1A1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | disclosed |